HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 5-iodoisoindoline-2-carboxylate → 5-Isopropoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 5-iodoisoindoline-2-carboxylate | HCID 57753580 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 5-Isopropoxy-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester | HCID 57753399 | — |
Reaction Steps
Prepared in analogy to Example A6(a) from 5-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A38(b)) and 2-propanol. White solid. MS (m/e): 222.1 ([M+H-Me2C═CH2]+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188139B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-ab8141574a814318a3560edeb15df78e |
| Source note | uspto-grants-2012_05 |