HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-Morpholin-4-yl-6-trifluoromethyl-2,3-dihydro-1H-isoindole hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-Morpholin-4-yl-6-trifluoromethyl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester | HCID 57753557 | — |
| Product | 5-Morpholin-4-yl-6-trifluoromethyl-2,3-dihydro-1H-isoindole hydrochloride | HCID 68822521 | — |
Reaction Steps
Prepared in analogy to Example A3(e) from 5-morpholin-4-yl-6-trifluoromethyl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. Off-white solid. MS (m/e): 273.0 ([M+H]+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188139B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-19e7bb2753c4462db344c3547f6c3211 |
| Source note | uspto-grants-2012_05 |