Hydrochloric Acid → HCID 68823337, compound

HRID 1930894Notes

Reaction equation

HRID 1930894 reaction equation
C(OC([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([CH2:17][C:18]([F:21])([F:20])[F:19])[CH:14]=2)[CH2:9]1)=O)(C)(C)C.[ClH:22]>>[ClH:22].[F:21][C:18]([F:19])([F:20])[CH2:17][C:13]1[CH:14]=[C:15]2[C:10](=[CH:11][CH:12]=1)[CH2:9][NH:8][CH2:16]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 57753244HCID 57753244, compound

Product 1

HCID 68823337HCID 68823337, compound

Procedure

Prepared in analogy to Example A3(e) from 5-(2,2,2-trifluoro-ethyl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl Ester and hydrochloric acid. Off-white solid. MS (m/e): 202.4 ([M+H]-+, 100%).

Sources & evidence

ORD record
ord-7076774e54c04ecd94da9153b07a8ba3
Source dataset
uspto-grants-2012_05
Patent number
US08188139B2

Reaction notes

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