Hydrochloric Acid → HCID 68822291, compound
Reaction equation
C(OC([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([N:17]3[CH2:22][CH2:21][CH:20]([O:23][CH3:24])[CH2:19][CH2:18]3)[CH:14]=2)[CH2:9]1)=O)(C)(C)C.[ClH:25]>>[ClH:25].[CH3:24][O:23][CH:20]1[CH2:19][CH2:18][N:17]([C:13]2[CH:14]=[C:15]3[C:10](=[CH:11][CH:12]=2)[CH2:9][NH:8][CH2:16]3)[CH2:22][CH2:21]1Participants
3
Procedure
Prepared in analogy to Example A3(e) from 5-(4-methoxy-piperidin-1-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. Brown solid. MS (m/e): 233.3 ([M+H]+, 100%).
Sources & evidence
- ORD record
- ord-fc060a4005a246e282455ee1be0f0e99
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08188139B2
Reaction notes
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