Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1930935Generated: October 31, 2026

Hydrochloric Acid → Rac-5-(tetrahydro-pyran-3-yl)-2,3-dihydro-1h-isoindole

https://huagongshe.com/reaction/1930935

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantRac-5-(tetrahydro-pyran-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753408—
ProductRac-5-(tetrahydro-pyran-3-yl)-2,3-dihydro-1h-isoindoleHCID 57753682—

Reaction Steps

Prepared in analogy to Example A3(e) from rac-5-(tetrahydro-pyran-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. Brown oil. MS (m/e): 204.3 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188139B2
Source datasetuspto-grants-2012_05
ORD IDord-f905ebd94e074b198f179f27ea9fdcaf
Source noteuspto-grants-2012_05