Hydrochloric Acid → HCID 11583103, compound

HRID 1931041Notes

Reaction equation

HRID 1931041 reaction equation
C(OC(=O)[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:38])/[CH:16]=[CH:17]/[C:18]1[CH:22]=[CH:21][N:20]([S:23]([C:26]2[CH:31]=[CH:30][C:29]([C:32]3[CH:33]=[N:34][CH:35]=[CH:36][CH:37]=3)=[CH:28][CH:27]=2)(=[O:25])=[O:24])[CH:19]=1)(C)(C)C.Cl>O1CCOCC1>[NH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15](=[O:38])/[CH:16]=[CH:17]/[C:18]1[CH:22]=[CH:21][N:20]([S:23]([C:26]2[CH:31]=[CH:30][C:29]([C:32]3[CH:33]=[N:34][CH:35]=[CH:36][CH:37]=3)=[CH:28][CH:27]=2)(=[O:25])=[O:24])[CH:19]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86613980HCID 86613980, compound

Product 1

HCID 11583103HCID 11583103, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The compound is prepared by treatment of (2-{(E)-3-[1-(4-pyridin-3-yl-benzenesulfonyl)-1H-pyrrol-3-yl]-allanoylamino}phenyl)-carbamic acid tert-butyl ester (compound A20) in dioxane with HCl. After the reaction is finished, the product precipitates from the reaction mixture.

Workup

  1. customthe product precipitates from the reaction mixture

Sources & evidence

ORD record
ord-89324d1a07074fc499e92996af3b1bd0
Source dataset
uspto-grants-2012_05
Patent number
US08188138B2

Reaction notes

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