HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 66646394, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 66646170 | HCID 66646170 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 66646394 | HCID 66646394 | — |
Reaction Steps
(E)-3-{3-[4-({[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-[2-(1H-indol-3-yl)-ethyl]-amino}methyl)-benzenesulfonyl]-1H-pyrrol-3-yl}-acrylic acid tert-butyl ester (compound D5) is dissolved in dichloromethane (50 ml). Then it is added TFA and the mixture is stirred for 26 hours. After evaporation, the residue is washed with toluene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188138B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-8d39f4164aa941778ea516d869b8d796 |
| Source note | uspto-grants-2012_05 |