反应详情

2-Acetylamino-7-benzoylamino-4-octenedioic acid dimethyl ester 142 was synthesised using standard solution-phase metathesis conditions (refer to section 7.5) from 6-acetoxy-2-benzoylamino-4-hexenoic acid methyl ester 141 and methyl-2-acetylamino-4-pentenoate 121a. The desired compound was obtained as a brown oil, and purified via column chromatography (SiO2; EtOAc:Hexane; 2:1).

1. custom2-Acetylamino-7-benzoylamino-4-octenedioic acid dimethyl ester 142 was synthesised