Myristanilide → HCID 24821533, compound

HRID 1931285Notes

Reaction equation

HRID 1931285 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[N+:8]([O-])=O.[C:11]1([NH:17][C:18](=O)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[C:11]1([N:17]2[C:2]3[CH:7]=[CH:6][N:5]=[CH:4][C:3]=3[N:8]=[C:18]2[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 69324MyristanilideHCID 27357814-Chloro-3-nitropyridine

Product 1

HCID 24821533HCID 24821533, compoundYield 34%

Procedure

Method B applied to 4-chloro-3-nitropyridine (79 mg, 0.5 mmol) and tetradecanoic acid phenylamide (182 mg, 0.6 mmol) afforded the title compound as viscous oil (64 mg, 34%). 1H NMR (DMSO) δ 0.83 (t, J=6.7Hz, 3H), 1.16-1.32 (m, 20H), 1.73 (p, J=6.7 Hz, 2H), 2.83 (t, J=6.7Hz, 2H). 7.63-7.71 (m, 6H), 8.56 (d, J=5.2Hz, 1H), 9.43 (s, 1H).

Sources & evidence

ORD record
ord-38884b08f0d7414a8361e4cf1cb35dd3
Source dataset
uspto-grants-2012_05
Patent number
US08188282B2

Reaction notes

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