Phenylhydrazine → Butanedioic acid, 1-(2-phenylhydrazide)

HRID 1931401Notes

Reaction equation

HRID 1931401 reaction equation
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9]1(=[O:15])[O:14][C:12](=[O:13])[CH2:11][CH2:10]1>ClCCl>[C:1]1([NH:7][NH:8][C:9]([CH2:10][CH2:11][C:12]([OH:14])=[O:13])=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 7516PhenylhydrazineHCID 7922Succinic anhydride

Product 1

HCID 232130Butanedioic acid, 1-(2-phenylhydrazide)

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2.5 g (23 mmol) of phenylhydrazine were dissolved in 30 ml of dichloromethane and 2.3 g (23 mmol) of succinic anhydride were added portionwise. The reaction mixture was stirred at room temperature for 16 h. The precipitated product was isolated by filtration and washed with dichloromethane. Yield: 4.2 g.

Workup

  1. customThe precipitated product was isolated by filtration
  2. washwashed with dichloromethane

Sources & evidence

ORD record
ord-bb021c5343984f89a1483ad1bf32c03f
Source dataset
uspto-grants-2012_05
Patent number
US08188291B2

Reaction notes

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