HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 2-[4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-1-(pyrrolidin-1-yl)-ethanone trifluoroacetic acid salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | [4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-acetic acid trifluoroacetic acid salt | HCID 44184931 | — |
| Product | 2-[4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-1-(pyrrolidin-1-yl)-ethanone trifluoroacetic acid salt | HCID 44185018 | — |
Reaction Steps
The title compound was prepared analogously as described in Example 30(d) from 100 mg (0.27 mmol) of [4-(4-fluoro-phenyl)-thiazol-2-ylamino]-acetic acid trifluoroacetic acid salt and 38.8 mg (0.54 mmol) of pyrrolidine. Yield: 17 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188291B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-9174c33fdcdc4afea4b3007f8be6b3f9 |
| Source note | uspto-grants-2012_05 |