HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Fluorophenyl)-5-nitropyridine → 6-(2-Fluorophenyl)pyridin-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Fluorophenyl)-5-nitropyridine | HCID 68537775 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-(2-Fluorophenyl)pyridin-3-amine | HCID 18955575 | — |
Reaction Steps
50 mg of 10% palladium on carbon were added to a solution of 3.2 g (14.66 mmol) of 2-(2-fluoro-phenyl)-5-nitro-pyridine in 250 ml of ethanol, and the reaction mixture was hydrogenated at atmospheric pressure for 3 h. After filtration, the solution was evaporated. Yield: 2.5 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188291B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-d19b76d01a564cf2a69b7f9ea02acc51 |
| Source note | uspto-grants-2012_05 |