HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 2-[6-(2-Fluoro-phenyl)-pyridin-3-yloxy]-1-(piperidin-1-yl)-ethanone trifluoroacetic acid salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | [6-(2-Fluoro-phenyl)-pyridin-3-yloxy]-acetic acid trifluoroacetic acid salt | HCID 68540719 | — |
| Product | 2-[6-(2-Fluoro-phenyl)-pyridin-3-yloxy]-1-(piperidin-1-yl)-ethanone trifluoroacetic acid salt | HCID 68536648 | — |
Reaction Steps
The title compound was prepared analogously as described in Example 30(d) from 100 mg (0.277 mmol) of [6-(2-fluoro-phenyl)-pyridin-3-yloxy]-acetic acid trifluoroacetic acid salt and 47.1 mg (0.554 mmol) of piperidine. Yield: 72 mg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188291B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-83928d1027ac4ac186c1cfc9e4c0e2d4 |
| Source note | uspto-grants-2012_05 |