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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1931441Generated: November 3, 2026

6-(2-Fluorophenyl)pyridin-3-ol → 3-(4-Methyl-2-phenyl-pyrimidin-5-yl)-1-(piperidin-1-yl)-propan-1-one

https://huagongshe.com/reaction/1931441

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(2-Fluorophenyl)pyridin-3-olHCID 23145770—
Reactant3-(4-Methyl-2-phenyl-pyrimidin-5-yl)-acrylic acidHCID 68538098—
Product3-(4-Methyl-2-phenyl-pyrimidin-5-yl)-1-(piperidin-1-yl)-propan-1-oneHCID 59152283—

Reaction Steps

The title compound was prepared from 3-(4-methyl-2-phenyl-pyrimidin-5-yl)-acrylic acid analogously as described in Example 15(b) and (c).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08188291B2
Source datasetuspto-grants-2012_05
ORD IDord-0901bfec70ff4c82878450f2c1b4ccfb
Source noteuspto-grants-2012_05