Carbamic chloride, N-methyl-N-phenyl- → HCID 44217947, compound

HRID 1931491Notes

Reaction equation

HRID 1931491 reaction equation
[C@H:1]1([NH:10][C:11]2[CH:20]=[CH:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([NH2:21])[CH:17]=3)[N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.[CH3:22][N:23]([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[C:24](Cl)=[O:25]>C(N(CC)CC)C>[C@H:1]1([NH:10][C:11]2[CH:20]=[CH:19][C:18]3[C:13](=[CH:14][CH:15]=[C:16]([NH:21][C:24](=[O:25])[N:23]([CH3:22])[C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=4)[CH:17]=3)[N:12]=2)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 57860958(R)-N2-Indan-1-yl-quinoline-2,6-diamine

Product 1

HCID 44217947HCID 44217947, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

The title compound, MS: m/e=409.7 (M+H+), was prepared in accordance with the general method 4 of example 16 from (R)—N2-indan-1-yl-quinoline-2,6-diamine, triethylamine and N-methyl-N-phenylcarbamoyl chloride.

Sources & evidence

ORD record
ord-6c231c1df8a04f6ea07591b28b102a90
Source dataset
uspto-grants-2012_05
Patent number
US08188284B2

Reaction notes

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