HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethylisoxazole-4-isocyanate → 1-(3,5-Dimethyl-isoxazol-4-yl)-3-[2-((R)-indan-1-ylamino)-quinolin-6-yl]-urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethylisoxazole-4-isocyanate | HCID 2736266 | — |
| Reactant | Magnesium gluconate anhydrous | HCID 11418570 | — |
| Reactant | (R)-N2-Indan-1-yl-quinoline-2,6-diamine | HCID 57860958 | — |
| Product | 1-(3,5-Dimethyl-isoxazol-4-yl)-3-[2-((R)-indan-1-ylamino)-quinolin-6-yl]-urea | HCID 44218269 | — |
Reaction Steps
The title compound, MS: m/e=414.6 (M+H+), was prepared in accordance with the general method 4 of example 16 from (R)—N2-indan-1-yl-quinoline-2,6-diamine and 3,5-dimethylisoxazol-4-yl isocyanate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188284B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-644d9274f6a54419ab48944c765145ac |
| Source note | uspto-grants-2012_05 |