2-Amino-6-methylpyridine → HCID 68915481, compound

HRID 1931520Notes

Reaction equation

HRID 1931520 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([NH:12][CH:13]1[C:21]3[C:16](=[CH:17][C:18]([F:22])=[CH:19][CH:20]=3)[CH2:15][CH2:14]1)[CH:6]=[CH:5]2.[NH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[C:26]([CH3:30])[N:25]=1>>[F:22][C:18]1[CH:17]=[C:16]2[C:21](=[CH:20][CH:19]=1)[CH:13]([NH:12][C:7]1[CH:6]=[CH:5][C:4]3[C:9](=[CH:10][CH:11]=[C:2]([NH:23][C:24]4[CH:29]=[CH:28][CH:27]=[C:26]([CH3:30])[N:25]=4)[CH:3]=3)[N:8]=1)[CH2:14][CH2:15]2

Participants

3

Reactant 2

HCID 157652-Amino-6-methylpyridineHCID 68630098HCID 68630098, compound

Product 1

HCID 68915481HCID 68915481, compound

Procedure

The title compound, yellow foam, MS: m/e=385.3 (M+H+), was prepared in accordance with the general method of example 66 from rac-(6-bromo-quinolin-2-yl)-(5-fluoro-indan-1-yl)-amine (see example 102, step A) and commercially available 2-amino-6-methyl-pyridine.

Sources & evidence

ORD record
ord-e8257f0aafc34618a4b3e2af7487b8c9
Source dataset
uspto-grants-2012_05
Patent number
US08188284B2

Reaction notes

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