HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-bromo-3,5-dichloro- → HCID 68518913, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-bromo-3,5-dichloro- | HCID 29766 | — |
| Reactant | Tert-butyl 3-oxopyrrolidine-1-carboxylate | HCID 471360 | — |
| Reactant | Magnesium | HCID 5462224 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68518913 | HCID 68518913 | — |
Reaction Steps
Preparation according to Preparation 5: 1-bromo-3,5-dichlorobenzene (5.0 g, 22.1 mmol), dry tetrahydrofuran (100 mL), magnesium turnings (0.54 g, 24.3 mmol) and 1-N-boc-3-pyrrolidinone (3.25 g, 17.7 mmol). Yield: 2.1 g. MS m/z (rel. intensity, 70 eV) 332 (M+, 1), 232 (17), 231 (23), 230 (22), 57 (bp).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188301B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-87b8202604c5419d9a4387120c94d5fa |
| Source note | uspto-grants-2012_05 |