2-Bromoethyl methyl ether → HCID 11647333, compound

HRID 1932321Notes

Reaction equation

HRID 1932321 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][C:20]=1[Cl:21])[O:5][CH2:6][C:7]1[N:8]=[CH:9][CH:10]=[C:11]2[C:15]([CH3:16])=[C:14]([CH3:17])[NH:13][C:12]=12.[CH3:22][O:23][CH2:24][CH2:25]Br>>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][C:20]=1[Cl:21])[O:5][CH2:6][C:7]1[N:8]=[CH:9][CH:10]=[C:11]2[C:15]([CH3:16])=[C:14]([CH3:17])[N:13]([CH2:25][CH2:24][O:23][CH3:22])[C:12]=12

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 67142891HCID 67142891, compound

Product 1

HCID 11647333HCID 11647333, compoundYield 70%

Procedure

In accordance with the same procedures as in Example 2, except for using 7-(3,4-dichlorophenoxymethyl)-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine prepared in Step 2 and 2-bromoethyl methyl ether, the titled compound was obtained as a white solid. (Yield: 70%)

Sources & evidence

ORD record
ord-26ffe1cffaa647a09e7ddb2ed7b646e2
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

Loading…