HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-N-methylaniline → (4-Fluorophenyl)-methyl-(3-nitropyridin-2-ylmethyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-N-methylaniline | HCID 68024 | — |
| Reactant | 2-(Bromomethyl)-3-nitropyridine | HCID 21831178 | — |
| Product | (4-Fluorophenyl)-methyl-(3-nitropyridin-2-ylmethyl)-amine | HCID 67141956 | 80% |
Reaction Steps
In accordance with the same procedures as in Step 1 of Preparation 2, except for using 2-bromomethyl-3-nitropyridine prepared in Step 2 of Preparation 1 and (4-fluorophenyl)-methylamine, the titled compound was obtained as yellow solid. (Yield: 80%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08188114B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-b6ea144c535a40659c4a51d37a54c6f8 |
| Source note | uspto-grants-2012_05 |