Iodoethane → 7-Chloro-1-ethyl-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine

HRID 1932338Notes

Reaction equation

HRID 1932338 reaction equation
[Cl:1][C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[NH:8][C:7]=12.I[CH2:14][CH3:15]>>[Cl:1][C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:14][CH3:15])[C:7]=12

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 116369277-Chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine

Product 1

HCID 117082897-Chloro-1-ethyl-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridineYield 42%

Procedure

In accordance with the same procedures as in Step 2 of Example 198, except for using 7-chloro-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridine prepared in Step 1 of Example 198 and iodoethane, the titled compound was obtained as a white solid. (Yield: 42%)

Sources & evidence

ORD record
ord-54639dfd200343678827ef3f1f8286c5
Source dataset
uspto-grants-2012_05
Patent number
US08188114B2

Reaction notes

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