1,8-Diazabicyclo(5.4.0)undec-7-ene → HCID 22467018, compound

Participants

Reaction Steps

After tetrahydrofuran (3 ml) and 1,8-diazabicyclo[5.4.0]-undeca-7-ene (25.5 mg, 0.168 mmol) was added to Compound (c) (30 mg, 0.14 mmol), the mixture was stirred at room temperature for an hour. The reaction solution was purified by silica gel column chromatography (10 ml, hexane:ethyl acetate=2:1) to give Compound (d) (23 mg, yield: 95.5%).

Provenance & Evidence