HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diphenylphosphinic chloride → HCID 15434705, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diphenylphosphinic chloride | HCID 73910 | — |
| Reactant | 5-Amino-3,4-dimethylisoxazole | HCID 88317 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 15434705 | HCID 15434705 | — |
Reaction Steps
N-(3,4-dimethyl-5-isoxazolyl)diphenyl phosphinic amide was prepared by the method of Example 1 with 3,4-dimethyl-5-amino isoxazole (0.22 g, 2.0 mmol), diphenyl phosphinic chloride (0.6 ml, 3.0 mmol) and pyridine (5 ml). Flash chromatography (5% methanol/chloroform) followed by recrystallization from ethyl acetate and hexanes provided 0.38 g (61%) of white crystals, m.p. 167-170° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06384261B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-fdf41f7785294986b86f43c79f7e060c |
| Source note | uspto-grants-2002_05 |