HCID 22466714, compound → HCID 22466551, compound

HRID 1935141Notes

Reaction equation

HRID 1935141 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([NH:9][C:10]2[C:19]3[C:14](=[C:15]([O:23][CH3:24])[CH:16]=[C:17]([N+:20]([O-])=O)[CH:18]=3)[N:13]=[CH:12][C:11]=2[C:25]#[N:26])[CH:5]=[CH:6][C:7]=1[CH3:8]>[Fe]>[NH2:20][C:17]1[CH:18]=[C:19]2[C:14](=[C:15]([O:23][CH3:24])[CH:16]=1)[N:13]=[CH:12][C:11]([C:25]#[N:26])=[C:10]2[NH:9][C:4]1[CH:5]=[CH:6][C:7]([CH3:8])=[C:2]([OH:1])[CH:3]=1

Participants

3

Reactant 1

HCID 22466714HCID 22466714, compound

Product 1

HCID 22466551HCID 22466551, compoundYield 76.6%

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

Using the method described in Example 196, 0.2 g of 4-(3-hydroxy-4-methyl-phenylamino)-8-methoxy-6-nitro-quinoline-3-carbonitrile and 0.1 g of iron was converted to 0.14 g of the title compound: MP=227° C. (dec)

Sources & evidence

ORD record
ord-a66668f432544d729ed4e649f0ab4ed5
Source dataset
uspto-grants-2002_05
Patent number
US06384051B1

Reaction notes

Loading…