Ethanol → 1-[4-[Methyl(propan-2-yl)amino]-2-propylcyclohexyl]-3-[[6-(trifluoromethyl)quinazolin-4-yl]amino]pyrrolidin-2-one
Reaction equation
[C:47](#[N:48])[CH3:49].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:44][CH2:45][OH:46].[Cl:29][c:30]1[n:31][cH:32][n:33][c:34]2[cH:35][cH:36][c:37]([C:40]([F:41])([F:42])[F:43])[cH:38][c:39]12.[NH2:1][CH:2]1[C:3](=[O:21])[N:4]([CH:7]2[CH:8]([CH2:18][CH2:19][CH3:20])[CH2:9][CH:10]([N:13]([CH3:14])[CH:15]([CH3:16])[CH3:17])[CH2:11][CH2:12]2)[CH2:5][CH2:6]1.[OH2:50]>>[NH:1]([CH:2]1[C:3](=[O:21])[N:4]([CH:7]2[CH:8]([CH2:18][CH2:19][CH3:20])[CH2:9][CH:10]([N:13]([CH3:14])[CH:15]([CH3:16])[CH3:17])[CH2:11][CH2:12]2)[CH2:5][CH2:6]1)[c:30]1[n:31][cH:32][n:33][c:34]2[cH:35][cH:36][c:37]([C:40]([F:41])([F:42])[F:43])[cH:38][c:39]12Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d261035ae0ce4a7192b7b4a6f3fab108
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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