Dichloromethane → 3-[3-Fluoro-4-(1,2,3,6-tetrahydropyridin-4-yl)phenyl]-5-(tetrazol-2-ylmethyl)-1,3-oxazolidin-2-one

HRID 193567Notes

Reaction equation

HRID 193567 reaction equation
[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[N:15]1[CH2:16][CH:17]=[C:18]([c:21]2[c:22]([F:39])[cH:23][c:24]([N:27]3[C:28](=[O:38])[O:29][CH:30]([CH2:32][n:33]4[n:34][cH:35][n:36][n:37]4)[CH2:31]3)[cH:25][cH:26]2)[CH2:19][CH2:20]1.[CH:40]([N:41]([CH2:42][CH3:43])[CH:44]([CH3:45])[CH3:46])([CH3:47])[CH3:48].[Cl:1][C:2]([O:3][CH:4]([Cl:5])[CH3:6])=[O:7].[Cl:49][CH2:50][Cl:51]>>[NH:15]1[CH2:16][CH:17]=[C:18]([c:21]2[c:22]([F:39])[cH:23][c:24]([N:27]3[C:28](=[O:38])[O:29][CH:30]([CH2:32][n:33]4[n:34][cH:35][n:36][n:37]4)[CH2:31]3)[cH:25][cH:26]2)[CH2:19][CH2:20]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 5213051-Chloroethyl chloroformateHCID 178519168HCID 178519168, compound

Product 1

HCID 218766133-[3-Fluoro-4-(1,2,3,6-tetrahydropyridin-4-yl)phenyl]-5-(tetrazol-2-ylmethyl)-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-fce66d6e9b1341ad99079ae823550315
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…