1-benzyl-5-(1-hydroxy-4,4-diphenylbutyl)-1H-imidazole → HCID 178520536, Verbindung

HRID 1935747Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1935747
C([N:8]1[C:12]([CH:13]([OH:29])[CH2:14][CH2:15][CH:16]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:11][N:10]=[CH:9]1)C1C=CC=CC=1>C(O)C.[Pd]>[NH:10]1[CH:11]=[C:12]([CH:13]([OH:29])[CH2:14][CH2:15][CH:16]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[N:8]=[CH:9]1

Komponenten

4

Edukt 1

HCID 148222901-benzyl-5-(1-hydroxy-4,4-diphenylbutyl)-1H-imidazole

Produkt 1

HCID 178520536HCID 178520536, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

3.0 g of 1-(3-benzyl-3H-imidazol-4-yl)-4,4-diphenylbutan-1-ol was dissolved in 150 ml of ethanol. The solution was hydrogenated at 45° C. with 10% palladium on carbon as catalyst for 5 hours. The reaction mixture was filtered, and the filtrate was evaporated to dryness under reduced pressure.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. customthe filtrate was evaporated to dryness under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-c1e0e2090f9c4ef590912f6ddddf96eb
Quelldatensatz
uspto-grants-2002_05
Patentnummer
US06388090B2

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