HCID 178419844, compound → HCID 178420191, compound

Participants

Reaction Steps

4-(3-benzyl-3H-inden-1-yl)-1H-imidazole was hydrogenated in ethanol using 10% palladium on charcoal as a catalyst. The mixture was filtered through Celite, and the solvent was evaporated. The crude 4-(3-benzyl-2,3-dihydro-1H-inden-1-yl)-1H-imidazole which was the mixture of the cis and trans diastereomers (the ratio 94:6) was purified by flash chromatography (elution with a dichloromethane—methanol gradient).

Provenance & Evidence