Sodium ion → 4-[5-(4-Benzyloxy-3-methoxy-phenyl)-6-butyl-pyridazin-3-yloxy]-piperidine-1-carboxylic acid tert-butyl ester

HRID 193630Notes

Reaction equation

HRID 193630 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1.[CH2:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[O:24][c:25]1[c:26]([O:42][CH3:43])[cH:27][c:28](-[c:31]2[c:32]([CH2:38][CH2:39][CH2:40][CH3:41])[n:33][n:34][c:35]([Cl:37])[cH:36]2)[cH:29][cH:30]1.[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[H-:16].[Na+:15]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:35]2[n:34][n:33][c:32]([CH2:38][CH2:39][CH2:40][CH3:41])[c:31](-[c:28]3[cH:27][c:26]([O:42][CH3:43])[c:25]([O:24][CH2:17][c:18]4[cH:19][cH:20][cH:21][cH:22][cH:23]4)[cH:30][cH:29]3)[cH:36]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 166653HydrideHCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylateHCID 866578214-(4-Benzyloxy-3-methoxy-phenyl)-3-butyl-6-chloro-pyridazine

Product 1

HCID 673747264-[5-(4-Benzyloxy-3-methoxy-phenyl)-6-butyl-pyridazin-3-yloxy]-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-2829905f6d184e8899029d69d14982ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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