HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Propanol, sodium salt (1:1) → 7-Propoxy-4-oxo-2-(2-propoxyphenyl)-3,4-dihydropyrimido[4,5-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Propanol, sodium salt (1:1) | HCID 23669363 | — |
| Reactant | 7-Methylsulphonyl-4-oxo-2-(2-propoxyphenyl)-3,4-dihydropyrimido[4,5-d]pyrimidine | HCID 135670752 | — |
| Product | 7-Propoxy-4-oxo-2-(2-propoxyphenyl)-3,4-dihydropyrimido[4,5-d]pyrimidine | HCID 135670762 | — |
Reaction Steps
In a similar manner to Example 63 reaction of 7-methylsulphonyl-4-oxo-2-(2-propoxyphenyl)-3,4-dihydropyrimido[4,5-d]pyrimidine (0.54 g) and sodium propoxide solution (from sodium, 0.17 g, and n-propanol, 25 ml) yielded the title compound, 0.19 g, m.p. 157-8° C. (recrystallized from n-propanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06391885B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-4bb0029a7dbc4fa8b5c2ace2eaf8e336 |
| Source note | uspto-grants-2002_05 |