HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → HCID 22462532, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | 3-(1-Methylpiperidin-4-yl)-1h-indol-5-amine | HCID 11831220 | — |
| Reactant | HCID 22462535 | HCID 22462535 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 22462532 | HCID 22462532 | — |
Reaction Steps
The title compound was prepared in a similar manner to Example 1 from 2,3-dichloro-4-(pyridin-4-yl)aniline (D9, 0.20 g, 0.85 mmole), 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole (D2, 0.15 g, 0.66 mmole), triphosgene (0.10 g, 0.34 mmole) and triethylamine (0.30 ml). This was obtained as a pink white solid (0.18 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06391891B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-260532b857ee40769c3848ba1950a93e |
| Source note | uspto-grants-2002_05 |