Magnesium → HCID 22462501, compound

HRID 1937008Notes

Reaction equation

HRID 1937008 reaction equation
[F:1][C:2]1[CH:11]=[CH:10][C:9]2[NH:8][C:7](=[O:12])[C:6]3[CH2:13][CH2:14][CH2:15][C:5]=3[C:4]=2[CH:3]=1.[Mg]>>[F:1][C:2]1[CH:11]=[CH:10][C:9]2[NH:8][C:7](=[O:12])[CH:6]3[CH2:13][CH2:14][CH2:15][CH:5]3[C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 5462224MagnesiumHCID 22462443HCID 22462443, compound

Product 1

HCID 22462501HCID 22462501, compoundYield 28%

Procedure

8-Fluoro-1,2,3,5-tetrahydrocyclopenta[c]quinolin-4-one (1.0 g, 4.9 mmol) and magnesium (1.2 g, 49.2 mmol) are reacted to form 280 mg (28%) of product analogously to Example 7.

Sources & evidence

ORD record
ord-b8f0655eef6c4b1081c6ac44b9225457
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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