Magnesium → HCID 18516404, compound

HRID 1937013Notes

Reaction equation

HRID 1937013 reaction equation
[F:1][C:2]1[C:11]2[NH:10][C:9](=[O:12])[C:8]3[CH2:13][CH2:14][CH2:15][C:7]=3[C:6]=2[CH:5]=[CH:4][CH:3]=1.[Mg]>>[F:1][C:2]1[C:11]2[NH:10][C:9](=[O:12])[CH:8]3[CH2:13][CH2:14][CH2:15][CH:7]3[C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 5462224MagnesiumHCID 22462475HCID 22462475, compound

Product 1

HCID 18516404HCID 18516404, compoundYield 56.8%

Procedure

Analogously to Example 7, 6-fluoro-1,2,3,5-tetrahydrocyclopenta[c]quinolin-4-one (494 mg, 2.4 mmol) is reacted with magnesium (1.22 g, 50.0 mmol) to form 280 mg (56%) of product.

Sources & evidence

ORD record
ord-9608637f8a74423887f842039152ff06
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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