Magnesium → HCID 22462492, compound

HRID 1937021Notes

Reaction equation

HRID 1937021 reaction equation
[N:1]1([C:7]2[CH:8]=[CH:9][C:10]3[C:11]4[CH2:20][CH2:19][CH2:18][C:12]=4[C:13](=[O:17])[NH:14][C:15]=3[CH:16]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[Mg]>>[N:1]1([C:7]2[CH:8]=[CH:9][C:10]3[CH:11]4[CH2:20][CH2:19][CH2:18][CH:12]4[C:13](=[O:17])[NH:14][C:15]=3[CH:16]=2)[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 5462224MagnesiumHCID 22462434HCID 22462434, compound

Product 1

HCID 22462492HCID 22462492, compound

Procedure

Analogously to Example 7, 7-(4-morpholinyl)-1,2,3,5-tetrahydrocyclopenta[c]quinolin-4-one (1.17 g, 4.3 mmol) is converted with magnesium (2.16 g, 86.6 mmol) into 660 mg (56%) of product.

Sources & evidence

ORD record
ord-e411d522fc5249afbeb544a3dd5301b4
Source dataset
uspto-grants-2002_05
Patent number
US06391887B1

Reaction notes

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