Hydrochloric Acid → HCID 22462740, compound

HRID 1937188Notes

Reaction equation

HRID 1937188 reaction equation
C(O)(=O)C(O)=[O:3].[C:7]([CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([C:19]2[S:23][C:22]3[CH:24]=[CH:25][CH:26]=[CH:27][C:21]=3[C:20]=2[CH2:28][C:29]2[CH:34]=[CH:33][C:32]([O:35][CH2:36][CH2:37][N:38]3[CH2:42][CH2:41][CH2:40][CH2:39]3)=[CH:31][CH:30]=2)=[CH:15][CH:14]=1)#[N:8].[ClH:43]>>[ClH:43].[NH2:8][C:7](=[O:3])[CH2:9][CH2:10][CH2:11][O:12][C:13]1[CH:14]=[CH:15][C:16]([C:19]2[S:23][C:22]3[CH:24]=[CH:25][CH:26]=[CH:27][C:21]=3[C:20]=2[CH2:28][C:29]2[CH:30]=[CH:31][C:32]([O:35][CH2:36][CH2:37][N:38]3[CH2:39][CH2:40][CH2:41][CH2:42]3)=[CH:33][CH:34]=2)=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 22462660HCID 22462660, compound

Product 1

HCID 22462740HCID 22462740, compoundYield 100%

Procedure

The free base of the above nitrile (Example 34, Part D) (0.15 g; 0.3 mmol) was combined with 7 mL of conc HCl and stirred at room temperature for 3 days. The mixture was concentrated under reduced pressure, and the product (0.16 g; 100% yield) was dried in vacuo overnight.

Workup

  1. concentrationThe mixture was concentrated under reduced pressure
  2. customthe product (0.16 g; 100% yield) was dried in vacuo overnight

Sources & evidence

ORD record
ord-02699f77d20945b2b5ad18c35e301281
Source dataset
uspto-grants-2002_05
Patent number
US06391901B1

Reaction notes

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