Methyl iodide → HCID 22463511, compound

HRID 1937238Notes

Reaction equation

HRID 1937238 reaction equation
N[C:2]12CC3(O)CC(CC(N)(C3)[CH2:3]1)C2.IC.CN[C:18]12CC3(O)CC(CC(NC)(C3)[CH2:19]1)C2.CN(C)[C:33]12CC3(O)CC(CC(N(C)C)(C3)[CH2:34]1)C2.[NH2:48][C:49]12[CH2:59][C:53]3([OH:60])[CH2:54][C:55]([OH:58])([CH2:57][C:51]([NH2:61])([CH2:52]3)[CH2:50]1)[CH2:56]2.I[CH2:63][CH3:64]>>[CH2:2]([NH:48][C:49]12[CH2:59][C:53]3([OH:60])[CH2:54][C:55]([OH:58])([CH2:57][C:51]([NH:61][CH2:18][CH3:19])([CH2:52]3)[CH2:50]1)[CH2:56]2)[CH3:3].[CH2:2]([N:48]([CH2:63][CH3:64])[C:49]12[CH2:59][C:53]3([OH:60])[CH2:54][C:55]([OH:58])([CH2:57][C:51]([N:61]([CH2:33][CH3:34])[CH2:18][CH3:19])([CH2:52]3)[CH2:50]1)[CH2:56]2)[CH3:3]

Participants

8

Reactant 6

HCID 6328Methyl iodideHCID 6340IodoethaneHCID 22463506HCID 22463506, compoundHCID 22463507HCID 22463507, compoundHCID 22463527HCID 22463527, compoundHCID 22463607HCID 22463607, compound

Product 2

HCID 22463511HCID 22463511, compoundHCID 22463550HCID 22463550, compound

Procedure

Reaction of 1,3-diamino-5-adamantanol with iodomethane provides 1,3-di(methylamino)-5-adamantanol, 1,3-di(dimethylamino)-5-adamantanol, etc. Reaction of 1,3-diamino-5,7-adamantanediol with iodoethane provides 1,3-di(ethylamino)-5,7-adamantanediol, 1,3-di(diethylamino)-5,7-adamantanediol, etc.

Workup

  1. customprovides

Sources & evidence

ORD record
ord-763f505fc1ff40859725ef033ada8030
Source dataset
uspto-grants-2002_05
Patent number
US06392104B1

Reaction notes

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