Hydrochloric Acid → HCID 12016975, compound

HRID 1937379Notes

Reaction equation

HRID 1937379 reaction equation
Cl[C:2]1[C:3]2[CH:10]=[CH:9][NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[Cl:11][C:12]1[CH:13]=[C:14]([CH:16]=[CH:17][CH:18]=1)[NH2:15].Cl>>[Cl:11][C:12]1[CH:13]=[C:14]([NH:15][C:2]2[C:3]3[CH:10]=[CH:9][NH:8][C:4]=3[N:5]=[CH:6][N:7]=2)[CH:16]=[CH:17][CH:18]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 79323-ChloroanilineHCID 53566827H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-

Product 1

HCID 12016975HCID 12016975, compound

Procedure

Following the procedure described in Example 1, the title compound was prepared from 4chloro-7H-pyrrolo[2,3-d]pyrimidine and 3-chloroaniline (3.4%). LC-MS: 245 (MH+); anal. RP18-HPLC RT: 3.74 min; HCl salt MP: 227-228° C.

Sources & evidence

ORD record
ord-97fba115755340388ce94faf1ea1c7e6
Source dataset
uspto-grants-2002_05
Patent number
US06395733B1

Reaction notes

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