Hydrochloric Acid → HCID 22460846, compound

HRID 1937380Notes

Reaction equation

HRID 1937380 reaction equation
[Cl:1][C:2]1[C:3]2[CH:10]=[CH:9][NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[NH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH3:18])[CH:13]=1.Cl>>[ClH:1].[N:5]1[C:4]2[NH:8][CH:9]=[CH:10][C:3]=2[C:2]([NH:11][C:12]2[CH:13]=[C:14]([CH3:18])[CH:15]=[CH:16][CH:17]=2)=[N:7][CH:6]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 7934m-ToluidineHCID 53566827H-Pyrrolo(2,3-d)pyrimidine, 4-chloro-

Product 1

HCID 22460846HCID 22460846, compound

Procedure

Following the procedure described in Example 1, the title compound was prepared from 4-chloro-7H-pyrrolo[2,3-d]pyrimidine and m-toluidine (34%). HRMS: Calcd. 225.1140, Found 225.1131; anal. RP18-HPLC RT: 3.45 min; HCl salt MP: 219° C.

Sources & evidence

ORD record
ord-293fd83e6c1a4e76b7b6a4cf855a9237
Source dataset
uspto-grants-2002_05
Patent number
US06395733B1

Reaction notes

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