Hydrochloric Acid → HCID 22460867, compound

HRID 1937381Notes

Reaction equation

HRID 1937381 reaction equation
[Cl:1][C:2]1[C:3]2[CH:10]=[CH:9][NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[NH2:11][C:12]1[CH:13]=[C:14]2[C:18](=[CH:19][CH:20]=1)[NH:17][CH:16]=[CH:15]2.Cl>>[ClH:1].[NH:17]1[C:18]2[C:14](=[CH:13][C:12]([NH:11][C:2]3[C:3]4[CH:10]=[CH:9][NH:8][C:4]=4[N:5]=[CH:6][N:7]=3)=[CH:20][CH:19]=2)[CH:15]=[CH:16]1

Participants

4

Procedure

Following the procedure described in Example 1, the title compound was prepared from 4-chloro-7H-pyrrolo[2,3-d]pyrimidine and 5-aminoindole (7%). HRMS: Calcd. 250.1093, Found 250.1081; anal. RP18-HPLC RT: 2.58 min; HCl salt MP: 218-221° C.

Sources & evidence

ORD record
ord-89678605f25b42189e65837d2aa852b4
Source dataset
uspto-grants-2002_05
Patent number
US06395733B1

Reaction notes

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