HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22460854, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | HCID 178422323 | HCID 178422323 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 22460854 | HCID 22460854 | 34% |
Reaction Steps
Utilizing a procedure analogous to that described in Example 16, this product was prepared in 34% yield from 4-hydroxy-7-methyl-pyrido[4,3-d]pyrimidine (1.0 eq) and m-chloroaniline (40.0 eq) in pyridine. The HCl salt was generated from the purified free base according to the procedure given in Example 1. (M.P. 255-256° C.; GC-MS: 270 (MH+); anal. RP18-HPLC RT: 4.05 min.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06395733B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-58567da7d1834ce8bdf19dbc08b3156b |
| Source note | uspto-grants-2002_05 |