HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → N2-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-N2,N4,N4-trimethyl-2,4-pyrimidinediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | 1,1'-(4-Chlorobutylidene)bis(4-fluorobenzene) | HCID 76820 | — |
| Reactant | N2,N4,N4-trimethyl-N2-(4-piperidinyl)-2,4-pyrimidinediamine | HCID 53854017 | — |
| Product | N2-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-N2,N4,N4-trimethyl-2,4-pyrimidinediamine | HCID 53914323 | — |
Reaction Steps
Using the same procedure as describe in example B.1 and adding a small amount of potassium iodide to the reaction mixture, intermediate 2 was reacted with 1,1′-(4-chlorobutylidene)bis[4-fluorobenzene] to form N2-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-N2,N4,N4-trimethyl-2,4-pyrimidinediamine (comp. 44, mp. 106.3° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06395742B1 |
| Source dataset | uspto-grants-2002_05 |
| ORD ID | ord-70a4ede76b9c4fc5bf4b2bc2bb840921 |
| Source note | uspto-grants-2002_05 |