Piperidine → HCID 178473333, compound

HRID 1937834Notes

Reaction equation

HRID 1937834 reaction equation
C1CCNCC1.CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1>CC(C)(C)[O-].Cc1ccccc1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.[Cl][Pd][Cl].[Na+]>CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(N4CCCCC4)cnc32)CC1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 10742688Ethyl 4-(3-bromo-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate

Product 1

HCID 178473333HCID 178473333, compoundYield 7%

Reagents, catalysts & solvents 3

HCID 23676156Sodium t-butoxideReagentHCID 10876480Bis(tri-o-tolylphosphine)palladium(II) DichlorideCatalystHCID 1140TolueneSolvent2×

Conditions

Temperature
100 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-a8d67585f94b455187bab5b5faebc1d5
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

Loading…