Piperidine → HCID 178525540, compound

HRID 1937835Notes

Reaction equation

HRID 1937835 reaction equation
C1CCNCC1.O=C(O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21>CC(C)(C)[O-].Cc1ccccc1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.[Cl][Pd][Cl].[Na+]>O=C(O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(N3CCCCC3)cc(F)cc21

Participants

6

Reactant 2

HCID 8082PiperidineHCID 11597294(R)-2-(5-broMo-4-(4-chlorobenzyl)-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

Product 1

HCID 178525540HCID 178525540, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 23676156Sodium t-butoxideReagentHCID 10876480Bis(tri-o-tolylphosphine)palladium(II) DichlorideCatalystHCID 1140TolueneSolvent2×

Conditions

Temperature
100 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-4908f938daac4350bc10d23b2f47f491
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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