Piperidine → HCID 178501343, compound

HRID 1937836Notes

Reaction equation

HRID 1937836 reaction equation
C1CCNCC1.COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(Br)c3C2)CN1C(=O)OCc1ccccc1>CC(C)(C)[O-].Cc1ccccc1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.[Cl][Pd][Cl].[Na+]>COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(N4CCCCC4)c3C2)CN1C(=O)OCc1ccccc1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 547543691-Benzyl 2-methyl (2S,4R)-4-((4-bromoisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate

Product 1

HCID 178501343HCID 178501343, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 23676156Sodium t-butoxideReagentHCID 10876480Bis(tri-o-tolylphosphine)palladium(II) DichlorideCatalystHCID 1140TolueneSolvent2×

Conditions

Temperature
100 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-dfc1a03f819747588f955c550bda6195
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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