Piperidine → HCID 178426457, compound

HRID 1937839Notes

Reaction equation

HRID 1937839 reaction equation
C1CCNCC1.Cc1cc(C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc(N)c1Br>CC(C)(C)[O-].Cc1ccccc1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.[Cl][Pd][Cl].[Na+]>Cc1cc(C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc(N)c1N1CCCCC1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 193962Etravirine

Product 1

HCID 178426457HCID 178426457, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 23676156Sodium t-butoxideReagentHCID 10876480Bis(tri-o-tolylphosphine)palladium(II) DichlorideCatalystHCID 1140TolueneSolvent2×

Conditions

Temperature
100 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-359676b73fc74fb38c725a1cfd490224
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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