Piperidine → HCID 138973475, compound

HRID 1937845Notes

Reaction equation

HRID 1937845 reaction equation
C1CCNCC1.O=C1Nc2ccc(Cl)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1>CC(C)(C)[O-].Cc1ccccc1.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.Cc1ccccc1P(c1ccccc1C)c1ccccc1C.[Cl][Pd][Cl].[Na+]>O=C1Nc2ccc(N3CCCCC3)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 64139Efavirenz

Product 1

HCID 138973475HCID 138973475, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 23676156Sodium t-butoxideReagentHCID 10876480Bis(tri-o-tolylphosphine)palladium(II) DichlorideCatalystHCID 1140TolueneSolvent2×

Conditions

Temperature
100 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-ceeefe06ac384aca83521f3ca3bd2ce5
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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