Piperidine → HCID 178501344, compound

HRID 1937850Notes

Reaction equation

HRID 1937850 reaction equation
C1CCNCC1.COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3c(F)ccc(Br)c3C2)CN1C(=O)OC(C)(C)C>CC(C)(C)[O-].CC(C1=C(P(C2CCCCC2)C2CCCCC2)C=C[CH]1)P(C(C)(C)C)C(C)(C)C.COCCOC.[CH]1C=CC=C1.[Fe].[Na+]>COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3c(F)ccc(N4CCCCC4)c3C2)CN1C(=O)OC(C)(C)C

Participants

6

Reactant 2

HCID 8082PiperidineHCID 1547282651-(tert-Butyl) 2-methyl (2S,4R)-4-((4-bromo-7-fluoroisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate

Product 1

HCID 178501344HCID 178501344, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 23676156Sodium t-butoxideReagentHCID 178437370HCID 178437370, compoundCatalystHCID 80711,2-DimethoxyethaneSolvent2×

Conditions

Temperature
80 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-2d24c512d1e3400dbf3a1d7f4d6f3c98
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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