Piperidine → HCID 178525540, compound

HRID 1937853Notes

Reaction equation

HRID 1937853 reaction equation
C1CCNCC1.O=C(O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cc(F)cc21>CC(C)(C)[O-].CC(C1=C(P(C2CCCCC2)C2CCCCC2)C=C[CH]1)P(C(C)(C)C)C(C)(C)C.COCCOC.[CH]1C=CC=C1.[Fe].[Na+]>O=C(O)C[C@H]1CCc2c1n(Cc1ccc(Cl)cc1)c1c(N3CCCCC3)cc(F)cc21

Participants

6

Reactant 2

HCID 8082PiperidineHCID 11597294(R)-2-(5-broMo-4-(4-chlorobenzyl)-7-fluoro-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid

Product 1

HCID 178525540HCID 178525540, compoundYield 0%

Reagents, catalysts & solvents 3

HCID 23676156Sodium t-butoxideReagentHCID 178437370HCID 178437370, compoundCatalystHCID 80711,2-DimethoxyethaneSolvent2×

Conditions

Temperature
80 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-4d3309117b4b47c8a2fe1b196669c3e9
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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