Piperidine → HCID 178523006, compound

HRID 1937856Notes

Reaction equation

HRID 1937856 reaction equation
C1CCNCC1.O=C(NCc1ccc(F)cc1)c1nc(Br)c2cccnc2c1O>CC(C)(C)[O-].CC(C1=C(P(C2CCCCC2)C2CCCCC2)C=C[CH]1)P(C(C)(C)C)C(C)(C)C.COCCOC.[CH]1C=CC=C1.[Fe].[Na+]>O=C(NCc1ccc(F)cc1)c1nc(N2CCCCC2)c2cccnc2c1O

Participants

6

Reactant 2

HCID 8082PiperidineHCID 223464015-bromo-N-(4-fluorobenzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamide

Product 1

HCID 178523006HCID 178523006, compoundYield 10%

Reagents, catalysts & solvents 3

HCID 23676156Sodium t-butoxideReagentHCID 178437370HCID 178437370, compoundCatalystHCID 80711,2-DimethoxyethaneSolvent2×

Conditions

Temperature
80 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-87bad93e5a3d4a7a82f0dd231ffffe13
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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