Piperidine → HCID 178501343, compound

HRID 1937872Notes

Reaction equation

HRID 1937872 reaction equation
C1CCNCC1.COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(Br)c3C2)CN1C(=O)OCc1ccccc1>C=CCc1ccccc1.CC(C)(C)[O-].CC(C)c1cccc(C(C)C)c1-n1ccn(-c2c(C(C)C)cccc2C(C)C)[c]1=[Pd][Cl].COCCOC.[K+]>COC(=O)[C@@H]1C[C@@H](OC(=O)N2Cc3cccc(N4CCCCC4)c3C2)CN1C(=O)OCc1ccccc1

Participants

6

Reactant 2

HCID 8082PiperidineHCID 547543691-Benzyl 2-methyl (2S,4R)-4-((4-bromoisoindoline-2-carbonyl)oxy)pyrrolidine-1,2-dicarboxylate

Product 1

HCID 178501343HCID 178501343, compoundYield 2%

Reagents, catalysts & solvents 3

HCID 23665647Potassium tert-butoxideReagentHCID 178438929HCID 178438929, compoundCatalystHCID 80711,2-DimethoxyethaneSolvent2×

Conditions

Temperature
25 °C

Workup

  1. additionNo procedure recorded

Sources & evidence

ORD record
ord-d625825ea5cd421c89ed2f6ed792537f
Source dataset
Pd_CN_Coupling_Informer_Library
Original link
View source

Reaction notes

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